Evaluation of a rapid whole-blood immunoassay to detect IgG antibodies against Helicobacter pylori

Introduction: Since individuals infected with H. pylori develop a local and systemic immune response, several diagnostic manufacturers have launched rapid H. pylori antibody tests. However, some of these tests are often used without sufficient evaluation. The purpose of this study was to compare the clinical performance of a commercially available rapid whole-blood immunoassay (gabControl® H. pylori [gabmed GmbH, Köln, Germany]) for the qualitative detection of IgG antibodies against H. pylori with the 13C-urea breath test (13C-UBT) serving as a reference method. Patients and Methods: In total 108 outpatients, w…