Gut-liver axis in cystic fibrosis: lack of association between intestinal inflammation and liver disease in adult cystic fibrosis patients after lung transplantation
E Halilbasic, K Staufer, D Schmid, A Brichta, P Jaksch, W Klepetko, H Vogelsang, M Trauner, L Kazemi-Shirazi · Zeitschrift für Gastroenterologie · 2016 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: The pathogenesis of cystic fibrosis-related liver disease (CFLD) is still unclear. Recent experimental studies support the role of intestinal inflammation in the development of CFLD. Aim: The aim of this study was to test the role of intestinal inflammation in the development of CFLD in adult lung-transplanted CF patients. Patients and Methods: Fecal calprotectin (FC) and serum antisaccharomices cerevisiae antibodies (ASCA), established markers of intestinal inflammation, were measured in 36 lung-transplanted CF patients (age 34 ± 8y, 42% male). Intestinal infection was excluded by stool cultures, ce…
