Maternal serum copeptin, MR-proANP and procalcitonin levels at 11 – 13 weeks gestation in the prediction of preeclampsia

Purpose: We investigated the potential value of maternal serum copeptin, midregional proatrial natriuretic peptide (MR-proANP) and Procalcitonin (PCT) levels at 11 – 13 weeks' gestation in the prediction of preeclampsia (PE) in a case-control study. Materials and methods: Maternal serum concentration of copeptin, MR-proANP and PCT were measured at 11 – 13 weeks' gestation in cases of PE (n = 35) and controls (n = 100). The PE group was divided into early-onset PE (EO-PE) and late-onset PE (LO-PE). From the regression model, the value in each case and control was expressed as a multiple of the expected median (Mo…