Vaginal progesterone combined with cervical pessary – a chance for pregnancies at risk for preterm birth?

Objective: We sought to compare patients treated with cervical pessary alone to patients treated with pessary plus vaginal progesterone. Study design: This is a pre- and post- intervention cohort study from a Preterm Labor Clinic where placement of a cervical pessary has been the standard treatment since 2008 for women at risk. From July 2011 onwards, vaginal progesterone (200 mg, suppositories) was prescribed in addition to the pessary whereby at risk patients (n = 55) and screening patients (n = 51) were treated at the time of diagnosis. Results: Delivery < 34 weeks occurred in 17/53 patients (32.1%) treated w…