Evaluation of risk factors in a large cohort of patients with recurrent miscarriage
K Vomstein, R Kuon, F Müller, T Goeggl, T Strowitzki, B Toth · Geburtshilfe und Frauenheilkunde · 2016 · Heft 10
Bibliografische Angaben
Zusammenfassung
Objective: The aim of this study was to identify the prevalence of risk factors for RM in a large study group. Methods: In total, n = 590 RM patients recruited between 03/2012 and 08/2015 underwent standardized diagnostics including screening for (i) anatomical malformations, (ii) endocrine dysfunctions (follicular and luteal phase), (iii) autoimmune disorders (antinuclear antibodies (ANA), anti- cardiolipin antibodies (ACL IgG/IgM), anti-ß2-glycoprotein ß2-IgG/IgM, lupus anticoagulant (LA)), (iv) prothrombotic changes (mutations in the factor V Leiden (FVL), prothrombin (PT), MTHFR gene, deficiencies of protein…