CareLit Fachartikel
Transitional Cell Tumor and p53
O. Yoshida · Aktuelle Urologie · 1996 · Heft S 1 · S. 59-60
Dokument
1067921
CareLit-ID
Jahr
1996
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Summary: It is now believed that about 50 % of all human cancers contain a mutation in p53, so hopes are high that molecular analysis will provide new insights into treating the disease. Several recent studies using PCR techniques have shown that p53 gene mutations are closely associated with high grade and/or stage urothelial cancers. The existence of p53 protein alterations in urothelial cancer, detected by imunohistochemistry seems to be one of the most promising prognostic markers. We have analysed the p53 tumor suppressor gene in 3 cases with bladder tumors developing after treatment for a renal pelvic or u…
Schlagworte
Urothelial cancer
p53 tumor suppressor gene
Prognostic marker
Recurrence
Tumor
After
Aktuelle Urologie
