Use of Mitomycin-C in refractive Laser surgery

Purpose: To evaluate the safety and efficacy of Mitomycin-C (MMC) in refractive laser surgery. Method: MMC 0.02% was used after primary PRK (n=1019) and PRK as a LASIK enhancement (n=12). The epithelium was removed after 20% alcohol solution applied for 20 seconds. PRK was done with NIDEK EC 5000. Bandage contact lens was applied. Antibiotic and steroid eye drops were given as usual. The preop and postop refractions and complications were measured. Results: In primary PRK, preop refraction was –7.75D in average. 86% of eyes were within 0.5D after surgery. Corneal haze happen in 34 eyes (3.14%) and only in 5 eyes…