Comparison of side-effect profile during standard and pegylated interferon treatment in chronic hepatitis C (CHC) patients

Aim: To compare the side-effects between the different therapeutic schemes. Method: 43 CHC patient's data were analyzed, who were treated with alfa-interferon (IFN) and ribavirin (RBV). The mean treatment period was 10,7 months in the standard group and 3,55 months in the pegylated group (by closing the summary). Results: 32 patients were treated with 3×3 MU IFN-alfa-2a/2b per week and 800 /1000mg RBV per day, the mean age was 46 years. 11 patient's dose was 180/135µg PEG-IFN-alfa-2a or 80–100µg PEG-IFN-alfa-2b per week and 800–1200mg RBV per day, the mean age was 47 years. Frequency of the side-effects (standar…