The Influence of Anisotropic Conductivity on the EEG Source Localization Investigated with an FEM Volume Conductor of an Animal Model

Purpose: Source localization based on EEG/MEG data is a widely used technique to investigate neuronal activity. It tries to localize focal sources (dipoles) in order to represent the external measured signal (EEG/MEG) solving an inverse problem. Thereby the accuracy of the results depends on the given volume conductor model. Volume conductor modeling using the Finite Element Method (FEM) opens the possibility of taking into account the anisotropic conductivity of, e.g., the white matter tracts. In our study we investigated the influence of this anisotropy on solving the forward and inverse problem using an anima…