Synchronized Oscillatory Activities of the Human Amygdala and Hippocampus during Emotional Learning in Epileptic Patients

The interactions of the amygdala with other brain regions during emotional learning have been studied by single cell and local field potential (LFP) recordings in animals. Recently, a synchronization of theta activity in the amygdalohippocampal network has been described as a correlate of conditioned fear. We investigated synchronized oscillatory activities during emotional learning in humans. Deep electrode ERP recordings (LFPs) were obtained from electrode arrays implanted in the human temporal lobe during invasive presurgical monitoring of N=26 epileptic patients. Contact sites were located within the amygdal…