Gamma Knife Thalamotomy and Pallidotomy in Medically Intractable Parkinsonian Tremor

Objective: Six patients with advanced Parkinson's disease (PD) underwent gamma knife radiosurgical procedures between October 1992 and September 1998. Methods: Four patients underwent thalamotomy, one patient was treated with pallidotomy. One patient received caudatotomy and thalamotomy. One woman and 5 men aged between 52 and 84 years (median 68 years) were followed-up over a period between 12 and 82 months (median 49 months) with MR and neurological means (UPDRS). Results: Of the four patients with thalamotomy three showed a good response while one remained stable [Unified Parkinson's Disease Rating Scale (UPD…