CareLit Fachartikel
Genetic pathway analysis of expression microarray data
S Spisák, O Galamb, F Sipos, B Molnár, Z Tulassay · Zeitschrift für Gastroenterologie · 2005 · Heft 05
Dokument
1071826
CareLit-ID
Jahr
2005
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Zusammenfassung
Background and Aims: mRNA expression analysis by microarrays can contribute to an enhanced diagnosis and to find altered biological pathways for explanation of the pathomechanism of the CRC. Our aim was to evaluate and interpret the chip analysis results according to the role of the differently expressed genes in genetic and biochemical pathways. Materials and Methods: Biopsy samples were taken from the pathological and routine part of the colon. Total RNA was extracted from frozen biopsy samples from 10 patients with colorectal adenocarcinoma. The mRNA fraction was amplified by T7 RNA amplification (Ambion Inc,…
Schlagworte
Database
Biopsy
Atlas
Cluster Analysis
Adenocarcinoma
Data Analysis
Diagnosis
ANOVA
Zeitschrift für Gastroenterologie
