CareLit Fachartikel
Functional MRI reveals enhanced somatosensory and impaired motor activation in orofacial dystonia
C Dresel, B Haslinger, F Castrop, A Wohlschläger, A.O Ceballos-Baumann · Aktuelle Neurologie · 2005 · Heft 10
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1072137
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Jahr
2005
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Zusammenfassung
Background: Etiology and pathophysiology of the focal dystonia blepharospasm which causes increased blinking frequency and involuntary eyelid spasms are unknown. In Meige syndrome, blepharospasm is associated with oromandibular dystonia. Previous studies have suggested deficient sensorimotor integration and cortical dysfunction in dystonia. We used fMRI to investigate cortical functional changes in these patients during skilled orofacial actions. Methods: We studied 13 patients with blepharospasm and 13 patients with Meige syndrome before and after botulinumtoxin (BTX) therapy compared to 13 matched controls. Wh…
Schlagworte
Blepharospasm
Basal Ganglia
Blinking
Movement
After
Aktuelle Neurologie
