Artificial Liver Support–Dosefinding Studies and In Vitro Comparison of Single Pass Albumin Dialysis (SPAD) with MARS and CVVHDF
IM Sauer, M Goetz, G Walter, I Steffen, U Stumborg, R Schwartlander, E Katenz, P Neuhaus · Zeitschrift für Gastroenterologie · 2006 · Heft 04
Bibliografische Angaben
Zusammenfassung
Aim: Single pass albumin dialysis (SPAD), the molecular adsorbents recirculation system (MARS) and continuous veno- venous hemodiafiltration (CVVHDF) were compared in vitro with regard to detoxification capacity. In an additional test setup dosefinding studies concerning the albumin concentration of SPAD were performed. Methods: Toxin-loaded human plasma was processed for 6.5 hours: For SPAD (n=6) and CVVHDF (n=6) a high-flux hollow fiber hemodiafilter (identical to the MARS filter) was used. In order to compare the MARS configuration with SPAD and CVVHDF we operated MARS in CVVHDF mode (n=6). Additionally, we p…
