Senna tea versus Erythromycin – two prokinetic agents for the assessment of large bowel motility in healthy volunteers using functional cine MRI

Introduction: The aim of our study was to develop a method to visualize and quantify large bowel motility using functional Cine MRI in comparing two different prokinetic agents. Material & Methods: 12 healthy individuals (5 male, 7 female, mean age 26.1y, SD 2.3y) underwent functional cine MRI prior to and after the administration of orally administered Senna tea(ST) or intravenously applied erythromycin(E). Two consecutive sets of repeated measurements were performed on a 1.5 T MRI system using coronal oriented, T2-weighted HASTE sequences(Matrix 256 + 207;FOV400mm;9–11slices; SL6mm), adjusted to the course of…