Working memory recruits mediotemporal networks: A combined intracranial EEG and fMRI study

Introduction: Traditionally, working memory is considered to be supported by prefrontal and parietal brain areas. However, recent clinical findings as well as results from fMRI and intracranial EEG suggest that mediotemporal structures, apart from their well-established involvement in long-term memory, may also contribute to working memory. Here, we aimed at directly examining whether and by which mechanism mediotemporal structures contribute to working memory. Methods: We have used a modified Sternberg task with serially presented faces as stimuli to assess intracranial EEG correlates of working memory in 11 pa…