FMRI-Paradigms for selective hippocampal activation

Aim: The aim of the present study was the development of an fMRI paradigm for a clinical setting for the selective activation of hippocampal structures. To reach this we applied stimuli of different categories (words, faces and pictures) to investigate the selective hippocampal activation during the encoding of these stimuli and investigated the lateralization of the respective activation. Methods: Three different paradigms were applied on healthy right-handed subjects. Each paradigm consisted of three different categories: blocks of new or repeated stimuli and a contrast condition. The stimuli were either words…