Neural correlates of cognition deficits in mild cognitive impairment and Alzheimer's disease as assessed by the CERAD neuropsychological test battery

Objective: Alzheimer's disease (AD) is characterized by severe cognitive deficits involving different cognitive domains such as memory decline, language deficits, and apraxia. Mild cognitive impairment (MCI) is supposed to represent a potential preclinical stage of the disease where distinct cognitive deficits occur. Although, memory impairment has been addressed in recent neuroimaging studies the neural substrates of most cognitive deficits in AD, which can be reliable be assessed by using the neuropsychological test battery of the Consortium to Establish a Register for Alzheimer's Disease (CERAD), remain unres…