Hemodynamic changes of carbetocin and oxytocin given as i.v. bolus on women undergoing Cesarean section

Aims: Postpartum hemorrhage (PPH) is a potentially life-threatening complication of both vaginal and cesarean delivery. The most frequent cause is uterine atony. The hemodynamic effects of oxytocin consists of a systemic vasodilatation with a decrease in maternal blood pressure, an increase in heart rate, cardiac output and pulmonary artery pressure, resulting in marked but short-lived hypotension and tachycardia. Methods: This study was undertaken to compare the effect of carbetocin versus oxytocin on maternal hemodynamic parameters as well as the effect on the myometrial contraction in a non-invasive setup dur…