Update on IOL materials and biocompatibility

The optic components of modern intraocular lenses (IOLs) are manufactured from rigid or foldable materials. Rigid lenses are made from an acrylic material, poly(methyl methacrylate) (PMMA), while foldable lenses are made of acrylic (hydrophilic or hydrophobic, according to the water content) or silicone materials. Besides ultraviolet absorbers (benzofenone or benzotriazole) other components are used in the manufacture of specialized lenses (e.g., light adjustable lens). Clinical studies showed appropriate uveal biocompatibility for the different IOL materials, while capsular biocompatibility is more dependent on…