High Dose versus Low Dose Corticoidsteroid Therapy during Ovarian Stimulation and Embryo Transfer in Women undergoing In Vitro Fertilisation-Embryo Transfer: A Prospective Randomi…
K Sator, E Bentz, C Tempfer, MO Sator, J Huber · Geburtshilfe und Frauenheilkunde · 2006 · Heft 09
Bibliografische Angaben
Zusammenfassung
Aims Immunologic factors play a crucial role in implantation and early embryonic development. Women with a history of multiple IVF-ET failures show a high prevalence of maternal autoantibody, elevated levels of natural killer cells and predominance of T-helper 1 cells. Some studies reported that immunosuppressive therapy is sufficient to reduce the percentage of these influencing factors. The aim of the study was to investigate whether a concomitant administration of high dose corticosteroid regimen during IVF-ET programs produces a higher pregnancy rate compared to a low dose corticosteroid regimen. Methods One…