Voxel-based morphometry reveals no signs of neurodegeneration in essential tremor
C. Daniels, M. Peller, S. Wolff, K. Alfke, K. Witt, C. Gaser, O. Jansen, H.R. Siebner, G. Deuschl · Aktuelle Neurologie · 2006 · Heft 09
Bibliografische Angaben
Zusammenfassung
Objective: Essential tremor (ET) is considered a monosymptomatic disease but has been shown recently to present with a number of motor and cognitive symptoms possibly indicating a generalized degenerative disease. Methods: We used voxel-based morphometry (VBM) based on high-resolution T1-weighted MRI to compare grey and white matter density between 27 ET patients and 27 age- and sex-matched healthy controls. 14 patients had only postural tremor while 13 patients showed additional intention tremor. Results: VBM failed to demonstrate regional decreases in grey and white matter volume in patients with ET. There was…
