Neuroprotection in normal pressure glaucoma

Open-angle glaucoma is a slowly progressive neurodegeneration of retinal ganglion cells and their axons with transynaptic degenerative within the central nervous system. Clinically, open-angle glaucoma is characterized by a specific pattern of optic nerve head and visual field damage that can lead to blindness. Low-pressure (also termed normal-tension) glaucoma is an open-angle subgroup in which untreated intraocular pressure is always in the statistically normal (mean 15.9±SD 2.9mmHg) range, usually ≤21mmHg. Population-based studies demonstrate that low-pressure glaucoma represents 20% to 39% of patients with o…