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Growth differentiation factor (GDF) -15– a novel biomarker to assess the extent of liver fibrosis in patients with chronic liver disease?

T Rädle-Hurst, E Herrmann, G Hess, S Zeuzem, F Lammert, J Rädle · Zeitschrift für Gastroenterologie · 2009 · Heft 01

Dokument
1074163
CareLit-ID
Jahr
2009
Publikation
PDF
nein
Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
T Rädle-Hurst, E Herrmann, G Hess, S Zeuzem, F Lammert, J Rädle
Ausgabe
Heft 01 / 2009
Seiten
–
Erschienen: 2009-01-20 00:00:00
ISSN
0044-2771
DOI
10.1055/s-0029-1191796

Zusammenfassung

Introduction: GDF-15 is known to provide prognostic information in patients with chronic heart failure. Patients with cirrhosis of the liver (LC) may also exhibit cardiac dysfunction that can be detected echocardiographically or by measuring the natriuretic peptide NT-proBNP. The aim of the study was to investigate the clinical value of GDF-15 in patients with chronic liver disease. Methods: Concentrations of NT-proBNP and GDF-15 were measured in 31 patients with LC and 33 patients with liver fibrosis (LF) and compared to clinical and echocardiographic parameters. Results: Mean levels of NT-proBNP and GDF-15 wer…

Schlagworte

GDF-15 Liver fibrosis NT-proBNP cardiac dysfunction liver cirrhosis Zeitschrift für Gastroenterologie