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Brain activation patterns during real locomotion in progressive supranuclear palsy

A Zwergal, C la Fougere, P Bartenstein, M Dieterich, M Strupp, T Brandt, K Jahn · Klinische Neurophysiologie · 2009 · Heft 03

Dokument
1074384
CareLit-ID
Jahr
2009
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
A Zwergal, C la Fougere, P Bartenstein, M Dieterich, M Strupp, T Brandt, K Jahn
Ausgabe
Heft 03 / 2009
Seiten
–
Erschienen: 2009-03-13 00:00:00
ISSN
1434-0275
DOI
10.1055/s-0029-1216086

Zusammenfassung

Objectives: Characterization of pathological changes in the supraspinal locomotor network in patients with progressive supranuclear palsy (PSP). Methods: 12 PSP patients and 16 age- and sex-matched healthy controls were included in the study. As a locomotion paradigm persons had to walk with a medium velocity in a basement floor providing uniform visual environment for 10 minutes. Then [18F]-Fluoro-desoxyglucose ([18F]-FDG, max. 200MBq) was injected intravenously while the subject continued walking for further 10 minutes. Imaging started 30 minutes after tracer injection. In all participants a second [18F]-FDG s…

Schlagworte

Klinische Neurophysiologie