Imbalanced metabolism between right and left temporoparietal junction predicts spatial bias in individuals with very early Alzheimer's disease
N Myers, P Redel, P Bublak, HJ Müller, H Förstl, A Drzezga, A Wohlschläger, K Finke, C Sorg · Klinische Neurophysiologie · 2009 · Heft 03
Bibliografische Angaben
Zusammenfassung
Deficits of spatial attention are present in early stages of Alzheimer's disease (AD). This raises the question of the neural correlates of spatial bias in early AD. In particular, we wanted to know to what extent the principle of contra-lesionality can explain this spatial biasing. To address this question, we used a paradigm derived from Bundesen's Theory of Visual Attention (TVA) and resting-state 18FDG-PET in a sample of 35 patients with mild AD (n=7) or mild cognitive impairment (n=28), to look for correlations between spatial bias and regional glucose metabolism. The patient's degree of spatial bias varied…
