CareLit Fachartikel

Anti-parietal cell autoantibodies (PCA) as serological marker of recurrent primary biliary cirrhosis after liver transplantation

S Ciesek, T Becker, J Klempnauer, MP Manns, CP Strassburg · Zeitschrift für Gastroenterologie · 2007 · Heft 01

Dokument
1075565
CareLit-ID
Jahr
2007
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
S Ciesek, T Becker, J Klempnauer, MP Manns, CP Strassburg
Ausgabe
Heft 01 / 2007
Seiten
–
Erschienen: 2007-01-23 00:00:00
ISSN
0044-2771
DOI
10.1055/s-2007-967846

Zusammenfassung

Liver transplantation (OLT) for primary biliary cirrhosis (PBC) is characterized by disease recurrence of up to one third of patients. The diagnosis of recurrence requires a cholestatic profile and a typical histology representing a challenge for transplant hepatologists. Antimitochondrial antibodies (AMA) establish the initial diagnosis, persist after OLT, and are thus of limited value for the diagnosis of recurrence. Aim of this analysis was to identify serological parameters associated with recurrent PBC. OLT performed between 1992 and 2006 at Hannover Medical School were evaluated retrospectively including h…

Schlagworte

After Diagnosis Transplantation Antibodies Autoantibodies Cholestasis Sepsis Zeitschrift für Gastroenterologie