High resolution small animal imaging with dedicated solenoid coils at a clinical 3T scanner
H Ittrich, K Peldschus, M Kaul, C Nolte-Ernsting, G Adam · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2007 · Heft 03
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Zusammenfassung
Purpose: To evaluate the potential of two new solenoid coils for imaging of in-vitro probes and in-vivo small animal imaging at a clinical 3T MR scanner. Methods: Two small animal 1-channel solenoid coils (rat coil (RC): 7cm Ø, 10cm length; mouse coil (MC): 4cm Ø, 9cm length, PFL Hamburg, Germany) were tested in a clinical 3T scanner (Philips Intera). SNR and coil homogeneity of typical imaging protocols (T2w, T2*w, voxel dimensions 500–70µm3) were analyzed in-vitro on different probes (cylindrical water phantoms, gelatine phantoms of SPIO-labeled stem cells (SPIO-rMSC) and antibody(AB)linked SPIO conjugates on…