Endotoxin, IL-6 and TNF-alpha plasmaconcentrations in patients with Crohn's disease

Aims: In the last decades the prevalence of Crohn's disease (CD) has increased. Numerous questions about the etiology, the pathomechanism and the treatment of CD still remain unanswered. Aims: In the present study we aimed to examine in our CD patients the changes of endotoxin and cytokine (TNF-α, IL-6) plasma levels during immunosuppressive therapy and jejunal nutrition, in addition to the routine laboratory parameters. Methods: At a time of clinical and laboratory manifestations of CD, after colonoscopy, CT enterography and histology we examined the plasma TNF-α, IL-6, endotoxin levels with ELISA before and du…