Determination of clarithromycin resistance and virulence genes of Helicobacter pylori in paraffin embedded samples
F Sükösd, A Ferencz, A Tiszai, ZF Kiss, Z Lénárd, I Német, L Kaiser, L Tiszlavicz, J Lonovics, T Mikó · Zeitschrift für Gastroenterologie · 2007 · Heft 05
Bibliografische Angaben
Zusammenfassung
Helicobacter pylori (H.p.) is the most common infectious agent worldwide. More than half of the world's population is infected. Despite of this, diseases attributable to H.p. are not so frequent. One explanation for this is the variability of the immune status of the host and the difference in bacterial virulence. Our aim was to determine the most important virulence genes of H. p. the Cag A and Vac A and its alleles occurrence in routinely examined samples, which were formalin fixed and paraffin embedded samples. A further task was to examine the existing resistance against the first choice antibiotic, clarithr…