Predictors of neoadjuvant anthracyline chemotherapy in breast cancer patients
PA Fasching, A Fritsche, MP Lux, MR Bani, T Papadopoulos, R Schulz-Wendtland, R Strick, MW Beckmann, A Dimmler · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2007 · Heft 08
Bibliografische Angaben
Zusammenfassung
Introduction: Neoadjuvant chemotherapy is a secure and effective therapy for patients with primary breast cancer. With regard to biomarkers, it provides a good opportunity to identify biomarkers with a predictive value. Several prognostic factors have been identified in breast cancer patients who received an adjuvant treatment. Aim of this study was to examine several biomarkers by immunohistochemistry and to correlate the expression with the pathological response rate. Patients and methods: A prospective cohort of 119 breast cancer patients was recruited for this study. All patients were treated with a neoadjuv…
