Long-term cost-effectiveness of insulin detemir versus NPH in type 2 diabetes patient: An evaluation in the German setting

Aims: To evaluate the long-term clinical and economic outcomes associated with therapy conversion to insulin detemir (Levemir, Novo Nordisk) from human insulin (NPH) in type 2 diabetes patients in the German setting. Material and Methods: A validated computer simulation model of type 2 diabetes was used to make long-term projections of clinical and cost outcomes based on patient characteristics and treatment effects from the German cohort of the PREDICTIVE observational study. The trial indicated that therapy conversion from NPH to insulin detemir was associated with a significant improvement in glycemic control…