CareLit Fachartikel

Treatment of postherpetic neuralgia with pregabalin under clinical practice conditions

G Ruf, F Leverkus, R Mallison, M Brasser · Aktuelle Neurologie · 2007 · Heft 09

Dokument
1076191
CareLit-ID
Jahr
2007
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Aktuelle Neurologie
Autor:innen
G Ruf, F Leverkus, R Mallison, M Brasser
Ausgabe
Heft 09 / 2007
Seiten
–
Erschienen: 2007-09-11 00:00:00
ISSN
0302-4350
DOI
10.1055/s-2007-987826

Zusammenfassung

Postherpetic neuralgia (PHN) profoundly affects health-related quality of life and functional status of patients. In addition to pain, often sleep disturbances or anxiety/depression are present (“triad of pain“). While the prevalence of PHN in herpes zoster patients is high (ca. 11%), it is difficult to treat and often refractory to available therapies. Pregabalin, a highly selective ligand for the alpha2-delta subunit protein of voltage-gated calcium channels, reduces release of excitatory neurotransmitters. It is approved for, among other indications, the treatment of peripheral and central neuropathic pain. W…

Schlagworte

Depression General Practice Physicians Calcium Channels Diagnosis Anxiety Calcium After Aktuelle Neurologie