11C-MET and 18F-FLT-PET as tracers for tumour activity in comparison to perfusion and diffusion MR imaging
R Ullrich, L Kracht, K Kesper, J Sobesky, A Jacobs · Aktuelle Neurologie · 2007 · Heft 09
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Zusammenfassung
Introduction: In the differentiation of malignant brain tumours the apparent diffusion coefficient (ADC) and the relative cerebral blood volume (rCBV) obtained by MRI have been evaluated1. Aim of this study was to investigate the relation between 11C-MET and 18F-FLT as amino acids for the assessment of proliferation in PET to rCBV respectively to the ADC. Marterial and methods: In total 19 patients with primary glioma were included. All patients underwent 11C-MET PET investigation, 10 patients 11C-MET and 18F-FLT PET. DW and PW images were performed in 17 of 19 patients. The relative cerebral blood volume (rCBV)…