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11C-MET and 18F-FLT-PET as tracers for tumour activity in comparison to perfusion and diffusion MR imaging

R Ullrich, L Kracht, K Kesper, J Sobesky, A Jacobs · Aktuelle Neurologie · 2007 · Heft 09

Dokument
1076212
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Jahr
2007
Publikation
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Metadaten
DOI
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Zeitschrift
Aktuelle Neurologie
Autor:innen
R Ullrich, L Kracht, K Kesper, J Sobesky, A Jacobs
Ausgabe
Heft 09 / 2007
Seiten
–
Erschienen: 2007-09-11 00:00:00
ISSN
0302-4350

Zusammenfassung

Introduction: In the differentiation of malignant brain tumours the apparent diffusion coefficient (ADC) and the relative cerebral blood volume (rCBV) obtained by MRI have been evaluated1. Aim of this study was to investigate the relation between 11C-MET and 18F-FLT as amino acids for the assessment of proliferation in PET to rCBV respectively to the ADC. Marterial and methods: In total 19 patients with primary glioma were included. All patients underwent 11C-MET PET investigation, 10 patients 11C-MET and 18F-FLT PET. DW and PW images were performed in 17 of 19 patients. The relative cerebral blood volume (rCBV)…

Schlagworte

Diffusion Blood Volume Blood Amino Acids After Aktuelle Neurologie