IL–6 and IL–1 enhance hepatic expression of ALR (Augmenter of Liver Regeneration)
R Dayoub, WE Thasler, C Hellerbrand, HJ Schlitt, TS Weiss · Zeitschrift für Gastroenterologie · 2008 · Heft 01
Bibliografische Angaben
Zusammenfassung
Liver Regneration is a complex process that involves many factors e.g. cytokines, growth factors and hormones. Among the hepatotrophic factors Augmenter of Liver Regeneration (ALR) has been shown to play an important role during liver regeneration. Additionally, increased ALR levels were detected for various types of acute liver diseases, and in addition we could find increased expression of ALR in livers from patients with cirrhosis, hepatocellular and cholangiocellular carcinoma. Furthermore, cytokines and growth factors have been demonstrated to play a significant role in cirrhosis and in hepatocellular carci…