In vivo permeability in patients with irritable bowel syndrome (IBS): correlation between increased colonic permeability and clinical symptoms in diarrhea-predominant IBS
K Gecse, R Róka, E Séra, A Rosztóczy, B Kiss, B Miklós, F Izbéki, J Fioramonti, L Pávics, L Bueno, T Wittmann · Zeitschrift für Gastroenterologie · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction and aims: Elevated intestinal and/or colonic permeability has been reported both in the post-infectious and in the sporadic forms of IBS, characteristically in the IBS-D subgroup of patients. The aim of this study was to evaluate a possible correlation between elevated colonic or intestinal permeability and clinical symptoms of IBS-D patients. Methods: IBS patients of the diarrhea (IBS-D, n=10) and of the constipation subgroup (IBS-C, n=13) fulfilling the Rome III criteria were studied and healthy subjects (n=8) served as controls. Small bowel and colonic permeability was evaluated by measuring 24 h…