The role of Schaffer's glands in the diagnosis of Barrett's esophagus
I Németh, L Tar, A Rosztóczy, F Izbéki, R Róka, K Gecse, FZ Kiss, F Sükösd, T Wittmann, T Mikó, L Tiszlavicz · Zeitschrift für Gastroenterologie · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Since specialised intestinal metaplasia (SIM) is uniquely regarded as praemalignant for esophageal adenocarcinoma the aim was to assess the distribution and frequency of additional Schaffer's glands (SGs) near SIM. Method: Between 2004 and 2007, 1149 consequtive lower esophageal biopsy cases of 826 patients were reclassified by classical histopathology focusing on SGs. Results: SGs were found in 198 cases. More than half of SGs' samples (103 cases) were found near SIM. Fifty-three from 63 SIM cases, 26 from 37 SIM cases and 1 from 9 SIM cases contained SGs with regenerative atypia (indefinite for dys…