Pantoprazole induced severe acute hepatitis

Introduction: Pantoprazole is a proton pump inhibitor, which is well tolerated and the incidence of adverse effects is relatively low. However, the incidence of pantoprozole induced hepatotoxicity is unclear. We present a case of acute severe hepatitis induced by pantoprazole that was reversible after discontinuation of the drug. Case report: A 52-year old Caucasian female was admitted to the gastroenterology department of our hospital with highly elevated transaminases and cholestasis parameters. One month prior to the onset of jaundice and the elevation of transaminases and cholestasis parameters the patient w…