Impact of the number of cycles per pulse on the efficiency of single-pulse transcranial magnetic stimulation
I Delvendahl, A Pechmann, C Ritter, T Bergmann, G Hartwigsen, B Gleich, N Gattinger, V Mall, H Siebner · Klinische Neurophysiologie · 2010 · Heft 03
Bibliografische Angaben
Zusammenfassung
Introduction: Waveform and current direction of transcranial magnetic stimulation (TMS) at the primary motor cortex essentially influence both amplitudes of motor evoked potentials (MEP) and resting motor threshold (RMT). We investigated the effect of concatenating multiple biphasic waves on these parameters. Methods: We measured RMT and input-output (IO) curves in 8 healthy volunteers using a burst stimulator prototype which allows the application of polyphasic waves consisting of 1 to 6 full biphasic sinus waves. For IO curves, we recorded motor evoked potentials (MEP) in steps of 10% RMT (ranging from 90% to…