Cardiovascular magnetic resonance imaging based comparison of myocardial involvement in a patient with LGMD 2C and a patient with Becker muscular dystrophy

Cardiac involvement in patients with a sarcoglycanopathy (limb-girdle muscular dystrophy, LGMD) and dystrophinopathy has been described previously. Here we present detailed cardiovascular magnetic resonance (CMR) data of a patient with γ-sarcoglycanopathy (LGMD 2C) and a patient with Becker muscular dystrophy (BMD). In the 24-year-old male patient with genetically proven BMD and minor skeletal muscle involvement, CMR cine-images demonstrated a slightly reduced left ventricular systolic function (EF 48%) with regional hypokinesia in the inferolateral wall. Contrast-imaging was performed using an inversion-recover…