Is there a role for dose painting within the prostate in the primal therapy of patients with localized prostate cancer using choline PET/CT, dynamic MRI and CAD or choline MRS?
M Schmuecking, S Perner, C Boltze, H Geyer, H Salz, F Finsterbusch, S Reske, TG Wendt, KH Kloetzer, C Marx, NM Blumstein · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2010 · Heft 04
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Zusammenfassung
Ziele: To evaluate the role of molecular/functional imaging for the delineation of intraprostatic subvolumes for radiation therapy (IMRT, dose painting) 26 patients received a 11C choline PET/CT study and 67 patients a MR study consisting of DCE-MRI and MRS. Methode: Inclusion criteria: pathological prostate-specific antigen values (PSA) and/or previously negative transrectal ultrasound guided biopsy. Acquisition of choline PET/CT images after intravenous injection of 1112±131 MBq 11C choline. Image fusion of colored parametric maps derived from DCE-MRI and MRS (single voxel spectroscopy, SVS; chemical shift ima…