Improved risk prediction of myocardial Infarction and coronary death based on quantification of subclinical coronary atherosclerosis – Results of the Heinz Nixdorf Recall study
R Erbel, S Möhlenkamp, S Moebus, N Lehmann, A Stang, A Schmermund, H Kälsch, D Grönemeyer, R Seibel, K Mann, R Siegrist, K Jöckel · Das Gesundheitswesen · 2010 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: Coronary artery calcium (CAC) has been suggested to improve prediction of coronary events beyond traditional risk factor assessment. We determined whether CAC scoring improves prediction of coronary events when added to traditional risk factor analysis in the general population. Methods: We used data of the Heinz Nixdorf Recall cohort study, including 4129 randomly selected subjects aged 59.4±7.7 years (53% women) without overt coronary artery disease at baseline (2000 to 2003). Traditional risk factors and CAC, measured by electron-beam computed tomography, were assessed. Participants were stratifie…