Angioarchitectural Changes in Acute and Chronic Cerebral Venous Thrombosis. A Synchrotron-based Micro- and Nano-CT Study
R Moritz, AC Langheinrich, M Yeniguen, M Kreisel, M Kampschulte, S Doenges, D Sedding, E Ritman, T Gerriets, E Stolz · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2010 · Heft 11
Bibliografische Angaben
Zusammenfassung
Aim: It is well known that recanalization of thrombosed cerebral sinuses occurs early but without marked influence on the long-term outcome. To better understand the mechanisms behind these clinical observations, we evaluated the sequels of chronic superior sagittal sinus (SSS) thrombosis in rats using micro- and nano-CT imaging. Material and Methods: SSS thrombosis was induced in 11 animals which were sacrificed after 6 hours (n=4) or 6 weeks (n=7). Eight sham-operated rats served as controls. After contrast perfusion brains were isolated and scanned using micro-, nano-, and synchrotron-based micro-CT. The cros…