CareLit Fachartikel
Role of NK cells in hepatic ischemia/reperfusion injury in mice
E Eggenhofer, MH Dahlke, E Geissler, HJ Schlitt, A Kroemer · Zeitschrift für Gastroenterologie · 2011 · Heft 01
Dokument
1078467
CareLit-ID
Jahr
2011
Publikation
PDF
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Metadaten
DOI
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zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: The liver is the primary organ affected by ischemia/reperfusion injury (IRI) after shock, surgical resection, or transplantation. In this context, myeloid leukocytes as well as T cells have been intensively studied, as they are thought to be primarily propagating the injury response. Interestingly, recent evidence implies NK cells in the pathogenesis of IRI as well. Nevertheless, the precise role of NK cells in IRI still remains enigmatic and clearly warrants further investigation. Methods: Wild-type (wt) C57BL/6, B6.Rag and Rag-common-γ-chain (Rag-γc) double-KO mice were subjected to 60 min of par…
Schlagworte
NK cells
ischemia reperfusion injury
liver regeneration
After
Transplantation
Blood
Zeitschrift für Gastroenterologie
