Endoscopic submucosal dissection (ESD) for wide-spread ‘en bloc resection’ in the esophagus – preliminary experience of 10 ESD's in 9 patients

Introduction: ESD is an advanced endoscopic ‘free hand’ which can provide an ‘en bloc’ tissue specimen of the lesion plus surrunding ‘safety zone’. However, experience in the esophagus is limited so far. Patients, Material & Method: From November 12, 2009 to November 3, 2010, 9 patients, ASA 1–4 were referred for ESD because of early cancer (n=6) or HG-IEN (n=2) in the distal esophagus (n=6) and gastro-esophageal junction (n=1; Siewert II). One patient had a symptomatic submucosal esophageal tumor. 2/7 had undergone unsuccessful or incomplete previous local EMR treatment for early cancer and Barrett's epithelium…