Differences in the proportional volume of different brain regions relative to the whole brain size

Introduction: Volumetric MRI studies have been widely used to evaluate differences between patient groups and healthy subjects or between men and women. However, little is known about the in vivo size of different brain regions in relation to the total intracranial volume (TIV). The aim of the present study was to evaluate volume differences in certain brain regions in relation to changes in TIV. Methods: Fifty-two healthy subjects underwent imaging with a 3D T1-weighted high-resolution isometric Magnetization Prepared Rapid Gradient Echo (MP-RAGE) scan on a 3T MRI scanner (Siemens Trio, Siemens Medical Solution…