CareLit Fachartikel

Safety issue of hydroxyethyl starch on neonatal renal function

D Klaffenbach, R Chakrabarti, HG Topf, W Rascher, M Schroth · Klinische Pädiatrie · 2011 · Heft 03

Dokument
1078732
CareLit-ID
Jahr
2011
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Pädiatrie
Autor:innen
D Klaffenbach, R Chakrabarti, HG Topf, W Rascher, M Schroth
Ausgabe
Heft 03 / 2011
Seiten
–
Erschienen: 2011-03-23 00:00:00
ISSN
0300-8630
DOI
10.1055/s-0031-1273906

Zusammenfassung

Objective: Hydroxyethyl starch (HES) is a synthetic fluid product commonly used in intensive and emergency care medicine. Controversy exists about its (side) effects on renal function. The aim was to test the impact of hydroxyethyl starch on the immature renal system of neonates in comparison to isotonic saline solution. Methods: In our retrospective analysis, 50 inborn neonates without known renal dysfunction suffering from severe hypovolemia were volume substituted according to neonatal standards. 25 neonates were treated with hydroxyethyl starch (4ml/kg hydroxyethyl starch 200/0.5) compared to 25 neonates tre…

Schlagworte

Glomerular filtration rate Hydroxyethyl starch Hypovolemia Neonate Shock Klinische Pädiatrie