CareLit Fachartikel

Viscum Album (mistletoe) extract inhibits growth of pediatric tumor cells in vitro

TJ Zuzak, M Bornschein, H Stephan, K Pajtler, J Eisenbraun, A Schramm, A Eggert · Klinische Pädiatrie · 2011 · Heft 05

Dokument
1078831
CareLit-ID
Jahr
2011
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Pädiatrie
Autor:innen
TJ Zuzak, M Bornschein, H Stephan, K Pajtler, J Eisenbraun, A Schramm, A Eggert
Ausgabe
Heft 05 / 2011
Seiten
–
Erschienen: 2011-05-05 00:00:00
ISSN
0300-8630
DOI
10.1055/s-0031-1277086

Zusammenfassung

Introduction: Viscum album (mistletoe) extract is a common complementary therapy used by cancer patients in Germany. Its safety is currently being explored in a German multicenter clinical trial in pediatric oncology, but little is known about its efficacy against pediatric tumor cells. Methods: A panel of tumor cell lines derived from several pediatric cancers (neuroblastoma, medulloblastoma, rhabdomyosarkoma, ALL, AML, lymphoma and retinoblastoma) were treated with Viscum album (abnobaVISCUM® Fraxini). Effects on apoptosis, cell cycle arrest and cell migration were investigated in vitro. Results: Viscum album…

Schlagworte

Tumor Apoptosis Germany Klinische Pädiatrie