Two-year outcomes and predictors in first-episode psychotic patients treated in community mental health services. Findings from the PICOS project

Background/Objectives: (1) To describe 2-year outcomes in a large clinical epidemiologic cohort of first-episode psychosis (FEP) patients, and (2) to explore the relative weight of premorbid adjustment (PA), duration of untreated psychosis (DUP), mode of onset, clinical and social characteristics at onset in predicting 2-year outcome. Methods: This study was conducted in the context of the Psychosis Incident Cohort Outcome Study (PICOS), a multisite naturalistic research on FEP patients treated within the public psychiatric sector in the Veneto Region (Italy) and which aims to develop a comprehensive predictive…