Incidence of HER-2 expression in gastric cancer during a one-year period in a single-center material
M Juhász, Z Tóth, D Kocsis, D Tóth, P Nagy, L Herszényi, I Pregun, P Miheller, K Lőrinczy, Z Tulassay · Zeitschrift für Gastroenterologie · 2011 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and aims: the expression of HER-2 receptor is strongly assocciated with more aggressive clinical course and worse prognosis in gastric carcinogenesis. In advanced gastric cancer, pilot studies showed promising results with the anti-HER-2 drug, trastuzumab. We evaluated the incidence of HER-2 receptor positivity in gastric cancer in our material of patients having gone through upper g.i. endoscopy (UGIE) over a one-year period in order to select potential candidates for anti-HER-2 therapy. Patients & Methods: the charts of patients with UGIE between Nov. 2009 and Febr. 2010 were reviewed. After collect…